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8.A.66 The Dystrophin (Dystrophin) Family.

Transmembrane protein CD4 and voltage-dependent Ca2+ channels (VDCC ; TC# 1.A.1.11.28) within neuromuscular synapses and at the surfaces of muscle cells in normal and dystrophin-mutant worms proved to be regulated by dystrophin (Zhan et al. 2014). Dystrophin is involved in modulating the confinement of VDCC within sarcolemmal membrane nanodomains in response to varying tonus of C. elegans body-wall muscles.

References associated with 8.A.66 family:

Leyva-Leyva, M., A. Sandoval, R. Felix, and R. González-Ramírez. (2018). Biochemical and Functional Interplay Between Ion Channels and the Components of the Dystrophin-Associated Glycoprotein Complex. J. Membr. Biol. [Epub: Ahead of Print] 29779049
Modarres, H.P. and M.R. Mofradt. (2014). Filamin: a structural and functional biomolecule with important roles in cell biology, signaling and mechanics. Mol. Cell Biomech 11: 39-65. 25330623
Nakamura, F., T.P. Stossel, and J.H. Hartwig. (2011). The filamins: organizers of cell structure and function. Cell Adh Migr 5: 160-169. 21169733
Zhan, H., R. Stanciauskas, C. Stigloher, K.K. Dizon, M. Jospin, J.L. Bessereau, and F. Pinaud. (2014). In vivo single-molecule imaging identifies altered dynamics of calcium channels in dystrophin-mutant C. elegans. Nat Commun 5: 4974. 25232639
Zhang, Z., H.A. Ledford, S. Park, W. Wang, S. Rafizadeh, H.J. Kim, W. Xu, L. Lu, V.C. Lau, A.A. Knowlton, X.D. Zhang, E.N. Yamoah, and N. Chiamvimonvat. (2016). Distinct subcellular mechanisms for the enhancement of the surface membrane expression of SK2 channel by its interacting proteins, α-actinin2 and filamin A. J. Physiol. [Epub: Ahead of Print] 27779751