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8.A.68.1.1
Endosomal membrane protein 70, TMN2p (EMP70 superfamily) with an N-terminal hydrophilic domain and a 9 TMS C-terminal domain. The hydrophilic N-terminal domain is in the lumen of the cytoplasmic membrane.  Suggested to be a channel or small molecule transporter (Schimmöller et al. 1998).

Accession Number:E7NFP9
Protein Name:Tmn2p
Length:672
Molecular Weight:76336.00
Species:Saccharomyces cerevisiae (strain FostersO) (Baker's yeast) [764101]
Number of TMSs:9
Substrate NONE

Cross database links:

Pfam: PF02990   

Gene Ontology

GO:0016021 C:integral to membrane

References (1)

[1] “Whole-genome comparison reveals novel genetic elements that characterize the genome of industrial strains of Saccharomyces cerevisiae.”  Borneman A.R.et.al.   21304888

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKRGVWLLIY CYATLTKGFS LPGLSPTTYH SGDEIPLLVN RLTPSIYFQH QDEEGNDVSG 
61:	DKEHFLYSYD YYNKRFHFCR PEHVEKQPES LGSVIFGDRI YNSPFQLNML EEKECVALCK 
121:	STIPGKDAKF INTLIKSGFF QNWLVDGLPA ARKAYDSRTK TNYYGTGFEL GFTDVKQTVD 
181:	GKAVPSTMEE LTSEASNEDV ILDARQPKNV KPNLVKTVEL PYFVNHFDIE VEFHDRGNDN 
241:	YRVVGVIVNP VSIERSSPGA CSTTGKPLIL DEDKDNEVYF TYSVKFVASD TVWATRWDKY 
301:	LHIYDPQIQW FSLINFSVIV ILLSSVVMHS LLRALKSDLA RYNELNLDNE FHEDSGWKLG 
361:	HGDVFRTPSK SMLLSILVGS GMQLFLMVMC SIFFAAVGLV SPVSRGSLPT VMFVLYALFG 
421:	FVGSYASMGV YKFFRGPYWK ANMILTPILL PGAIFLLIVI MNFFLLFAHS SGVIPARSLF 
481:	FIILLWFLVS VPLSFAGSIV AHKQCNWDEH PTKTNQIARQ IPYQPWYLRT AQATLIAGIF 
541:	SFGSIAVELY FIYSSLWFNK IFYMFGFLLF SFLLLTLTTS LVTILITYYS LCLENWLWQW 
601:	RSFIIGGLGC SIHTFIHSIL FTKFKLGGVI TVVLYLGYSL IISALCCVVT GAIGFFSSMF 
661:	FIRKIYSAIK VE