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8.A.83.1.1
Shisa6 of 500 aas and 2 TMSs, one N-terminal and one at position 176 - 195.  Interacts with AMPA receptors (TC# 1.A.10) at post synaptic sites and prevents desensitization (Klaassen et al. 2016).

Accession Number:Q6ZSJ9
Protein Name:Protein shisa-6 homolog
Length:500
Molecular Weight:55764.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Membrane1 / Single-pass type I membrane protein2
Substrate NONE

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MALRRLLLLL LLSLESLDLL PSVHGARGRA ANRTLSAGGA AVGGRRAGGA LARGGRELNG 
61:	TARAPGIPEA GSRRGQPAAA VAAAASAAVT YETCWGYYDV SGQYDKEFEC NNSESGYLYC 
121:	CGTCYYRFCC KKRHEKLDQR QCTNYQSPVW VQTPSTKVVS PGPENKYDPE KDKTNFTVYI 
181:	TCGVIAFVIV AGVFAKVSYD KAHRPPREMN IHRALADILR QQGPIPIAHC ERETISAIDT 
241:	SPKENTPVRS SSKNHYTPVR TAKQTPEKPR MNNILTSATE PYDLSFSRSF QNLAHLPPSY 
301:	ESAVKTNPSK YSSLKRLTDK EADEYYMRRR HLPDLAARGT LPLNVIQMSQ QKPLPRERPR 
361:	RPIRAMSQDR VLSPDRGLPD EFSMPYDRIL SDEQLLSTER LHSQDPLLSP ERTAFPEQSL 
421:	SRAISHTDVF VSTPVLDRYR MSKMHSHPSA SNNSYATLGQ SQTAAKRHAF ASRRHNTVEQ 
481:	LHYIPGHHTC YTASKTEVTV