TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*8.A.87.1.1









AS160, TBC1 domain family member 4 of 1298 aas and 3 or 4 TMSs, one N-terminal and 3 C-terminal.  It regulates energy utilization and promotes translocation of various transporters from an intracellular site to the plasma membrane.  These include the glucose transporter, GLUT4, and several proteins involved in fatty acid transport (Mikłosz et al. 2016).

Eukaryota
Metazoa
AS160 of Homo sapiens
*8.A.87.1.2









Tbc domain protein of 745 aas and 2 or 3 TMSs

Eukaryota
Fungi
Tcb domain protein of Sporothrix insectorum
*8.A.87.1.3









TBC1 homologue of 1159 aas and 3 or 4 TMSs. 

Eukaryota
Metazoa
TBC1 homologue of Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
*8.A.87.1.4









TBC1D1 of 1168 aas and 3 or 4 TMSs as for TBC1D4 which is 50 % identical to TBC1D1 (Cartee 2015).

Eukaryota
Metazoa
TBC1D1 of Homo sapiens
*8.A.87.1.5









Small G-protein signaling modulator, Sgsm3, (Cip85, Rutbc3) of 749 aas.  Interacts with connexin 43 and probably regulates gap junctional permeability (Giepmans 2006).

Eukaryota
Metazoa
Cip85 of Homo sapiens
*8.A.87.1.6









NOV (CCN3, NOVH, IGFBP9) of 357 aas and 3 putative TMSs.  Binds and may regulate Connexin 43, influencing gap junctional permeability (Giepmans 2006).

Eukaryota
Metazoa
NOV of Homo sapiens