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8.A.9.2.3
CD98hc, heavy chain of the heterodimeric CD998 (CG2791) amino acid transporter; involved in cell fusion, cell adhesion, TOR signalling, and amino acid transprot via LAT1 and LAT2 (see TC# 2.A.3.8.32) (Reynolds et al. 2009). CD98hc combines with one of six CD98lc proteins to regulate vascular smooth muscle cell proliferation in atherosclerosis (Baumer et al. 2017).

Accession Number:Q9VHX9
Protein Name:CD98 heavy chain, isoform A
Length:565
Molecular Weight:62677.00
Species:Drosophila melanogaster (Fruit fly) [7227]
Number of TMSs:1
Substrate NONE

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVQDEKAAHA DGADEQMLGS NGVEDKLAER RDEVKFIKGD HQNGDAKIDI GTVNGGKPAF 
61:	TGMSKEELMK YANDPFWVRL RWIFFVCFWA IWVGMLVGAI LIIIGAPKCA APQPLPWYKR 
121:	GPHAKFASVE TCRPEDVQVA KKLVSAGAIY ELPAALTYDV KKPEVEEKIK HLVALYQGSD 
181:	TRVILDLTPN YAAKNSQLVQ DAIANPEKRS AFVWVSGGKA LPNNWLKVGG NRSAWEKVGD 
241:	NYVLSQFEDG YYDLKMNSTI IRNEFGAVLK HLVALGVRGF RLKNTKFFAL FDSLEDEQIS 
301:	SSPKDFSLGP NEYGFYSHRQ TTFLSGLGDV LYDYLSIVKN ASDEAFFSVA EDVMEPQVYQ 
361:	LSGDSGAYGI DLPMYGNFVK VLSKSKPDTS LQKELDNTLA QSGTDSWLQW NLADVYVDTP 
421:	QDPSALAMFL SLLPGVPVVA VDAVAYQNVT EETYRQITSL RKTASYMHGN LNLYQADPLV 
481:	AFSRIKSGNP GYFVIFNPTE LPQASNFTIP DNLPDKMTVS YFSEQYNNNM DNSGKVAHAG 
541:	RVNLKDLKVA PHSSIILTYV PVKAE