TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*8.A.90.1.1









Uroplakin 2, UPK2, of 184 aas and 2 or 3 TMSs, 1 or 2 N-terminal and 1 C-terminal.  UPK2 is a component of the asymmetric unit membrane (AUM), a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play a role in regulating the assembly of the AUM which regulates channel activities (see 8.A.40.1.1) (Chicote et al. 2017).

Eukaryota
Metazoa
UPK2 of Homo sapiens
*8.A.90.1.2









UPK2 of 179 aas and 1 - 3 TMSs, possibly 0, 1 or 2 TMSs N-terminal and 1 C-terminal.

Eukaryota
Metazoa
UPK2 of Salmo salar (Atlantic salmon)
*8.A.90.1.3









UPK2 of 188 aas and 2 TMSs, one N-terminal and one C-terminal

Eukaryota
Metazoa
UPK2 of Lepisosteus oculatus (Spotted gar)
*8.A.90.2.1









Uroplakin 3a (UKP3a) of 287 aas and 2 probable TMSs, one N-terminal and one C-terminal (Chicote et al. 2017).

Eukaryota
Metazoa
UKP3a of Homo sapiens
*8.A.90.2.2









Uroplakin 3b, UPK3B, of 320 aas

Eukaryota
Metazoa
UPK3b of Homo sapiens
*8.A.90.2.3









Uroplakin 3c, UPK3C, of 263 aas and 2 TMSs, one N-terminal and one C-terminal.

Eukaryota
Metazoa
UPK3c of Homo sapiens