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8.B.1.1.7
AahII; neurotoxin 2 of 85 aas. Scorpion α-toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active against mammals.

Accession Number:P01484
Protein Name:Alpha-mammal toxin AaH2
Length:85
Molecular Weight:9548.00
Species:Androctonus australis (Sahara scorpion) [6858]
Location1 / Topology2 / Orientation3: Secreted1
Substrate NONE

Cross database links:

Structure:
1AHO   1PTX   1SEG   4AEI     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNYLVMISLA LLFVTGVESV KDGYIVDDVN CTYFCGRNAY CNEECTKLKG ESGYCQWASP 
61:	YGNACYCYKL PDHVRTKGPG RCHGR