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8.B.12.1.1
The spider toxin Tx2-5 (Matavel et al., 2009).

Accession Number:O76199
Protein Name:U4-ctenitoxin-Pn1a
Length:82
Molecular Weight:8856.00
Species: [6918]
Location1 / Topology2 / Orientation3: Secreted1
Substrate NONE

Cross database links:

Gene Ontology

GO:0005576 C:extracellular region
GO:0019871 F:sodium channel inhibitor activity
GO:0009405 P:pathogenesis

References (5)

[1] “Cloning of cDNAS encoding neurotoxic peptides from the spider Phoneutria nigriventer.”  Kalapothakis E.et.al.   9839668
[2] “The purification and amino acid sequences of four Tx2 neurotoxins from the venom of the Brazilian 'armed' spider Phoneutria nigriventer (Keys).”  Cordeiro M.N.et.al.   1397265
[3] “Structure and activity analysis of two spider toxins that alter sodium channel inactivation kinetics.”  Matavel A.et.al.   19231838
[4] “Comparison of the partial proteomes of the venoms of Brazilian spiders of the genus Phoneutria.”  Richardson M.et.al.   16278100
[5] “Isolation of neurotoxic peptides from the venom of the 'armed' spider Phoneutria nigriventer.”  Rezende L. Jr.et.al.   1801316

External Searches:

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Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKVAILFLSI LVLAVASESI EESRDDFAVE ELGRATCAGQ DQTCKVTCDC CGERGECVCG 
61:	GPCICRQGNF LIAWYKLASC KK