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8.B.14.1.1
Sea anemone Class 1 toxin, BgK of 37 aas (blocks channels containing Kv1 subunits); the 3-d structure known (1BGKA) (Aneiros et al. 1993).

Accession Number:P29186
Protein Name:Potassium channel toxin Bgk
Length:37
Molecular Weight:4282.00
Species:Bunodosoma granulifera (Sea anemone) [31164]
Location1 / Topology2 / Orientation3: Secreted1
Substrate NONE

Cross database links:

Pfam: PF01549   

Gene Ontology

GO:0005576 C:extracellular region
GO:0042151 C:nematocyst
GO:0019870 F:potassium channel inhibitor activity
GO:0009405 P:pathogenesis

References (6)

[1] “A potassium channel toxin from the secretion of the sea anemone Bunodosoma granulifera. Isolation, amino acid sequence and biological activity.”  Aneiros A.et.al.   8098956
[2] “A potassium-channel toxin from the sea anemone Bunodosoma granulifera, an inhibitor for Kv1 channels. Revision of the amino acid sequence, disulfide-bridge assignment, chemical synthesis, and biological activity.”  Cotton J.et.al.   9063464
[3] “On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures.”  Dauplais M.et.al.   9020148
[4] “A potassium channel toxin from the secretion of the sea anemone Bunodosoma granulifera. Isolation, amino acid sequence and biological activity.”  Aneiros A.et.al.   8098956
[5] “A potassium-channel toxin from the sea anemone Bunodosoma granulifera, an inhibitor for Kv1 channels. Revision of the amino acid sequence, disulfide-bridge assignment, chemical synthesis, and biological activity.”  Cotton J.et.al.   9063464
[6] “On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures.”  Dauplais M.et.al.   9020148
Structure:
1BGK     

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FASTA formatted sequence
1:	VCRDWFKETA CRHAKSLGNC RTSQKYRANC AKTCELC