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8.B.14.2.1
Matrix metalloprotease 23 (MMP23), with a C-terminal K channel blocking Toxin Domain, TxD (residues 254 - 290; 37 aas). The NMR structure of the 37 aa toxin domain is available (2K72_A) (Rangaraju et al., 2010).

Accession Number:O88676
Protein Name:Matrix metalloproteinase-23
Length:391
Molecular Weight:44451.00
Species:Mus musculus (Mouse) [10090]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Endoplasmic reticulum membrane1 / Single-pass type II membrane protein2
Substrate NONE

Cross database links:

Genevestigator: O88676 O88676
HEGENOM: HBG447028 HBG447028

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGCRACLRPE ASGAVQGRWL GAALSGLCLL SALALLEWLG APTETAWRAA QGNVDAPNVG 
61:	SSTAQVPRLL TMSVTRRRRY TLTPARLRWD HFNLTYRVLS FPRNLLSPEE TRRGLAAAFR 
121:	MWSDVSPFSF REVAPERPSD LKIGFYPVNH TDCLVSAVHH CFDGPTGELA HAFFPPHGGI 
181:	HFDDSEYWVL GPTRYSWKKG VWLTNLVHVA AHEIGHALGL MHSQQDQALM HLNATLRGWK 
241:	ALSQDELWGL HRLYGCLDRI FVCASWARKG FCDVRQRLMK RLCPRSCDFC YEFPFPTVAT 
301:	TTSPTRTKTR LVREGRNMTF HCGQKILHKK GKVYWYKDQE PLEFSYPGYL ALGEAQLSII 
361:	ANAVNEGTYT CVVRRHQRVL STYSWRVRVR N