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8.B.17.1.1
The Sea Anemone peptide type III neurotoxin, ShI (Fogh et al., 1990), 3-d structure known (1SHI-A).

Accession Number:P19651
Protein Name:Neurotoxin 1
Length:48
Molecular Weight:5143.00
Species:Stoichactis helianthus (Carribean sea anemone) [6123]
Location1 / Topology2 / Orientation3: Secreted1
Substrate NONE

Cross database links:

Pfam: PF00706   

Gene Ontology

GO:0005576 C:extracellular region
GO:0042151 C:nematocyst
GO:0019871 F:sodium channel inhibitor activity
GO:0009405 P:pathogenesis
GO:0009966 P:regulation of signal transduction

References (5)

[1] “Isolation, characterization, and amino acid sequence of a polypeptide neurotoxin occurring in the sea anemone Stichodactyla helianthus.”  Kem W.R.et.al.   2568126
[2] “Chemical synthesis of a neurotoxic polypeptide from the sea anemone Stichodactyla helianthus.”  Pennington M.W.et.al.   1981881
[3] “Limited proteolysis study of structure-function relationships in Sh I, a polypeptide neurotoxin from a sea anemone.”  Monks S.A.et.al.   7913833
[4] “Solution structure of neurotoxin I from the sea anemone Stichodactyla helianthus. A nuclear magnetic resonance, distance geometry, and restrained molecular dynamics study.”  Fogh R.H.et.al.   1973932
[5] “Refined structure in solution of the sea anemone neurotoxin ShI.”  Wilcox G.R.et.al.   7901218
Structure:
1SH1   1SHI   2SH1     

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FASTA formatted sequence
1:	AACKCDDEGP DIRTAPLTGT VDLGSCNAGW EKCASYYTII ADCCRKKK