TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*8.B.25.1.1









Viral protein inhibitor of the TAP ABC transporter (TC# 3.A.1.209.1) of 98 aas and 2 TMSs (Verweij et al. 2008).

Viruses
Herpesvirales
Glycoprotein N of Suid herpesvirus 1 (SuHV-1) (Pseudorabies virus)
*8.B.25.1.2









GN polyprotein protein product, UL49.5, of 96 aas and 2 TMSs. It is an inhibitor of the transporter associated with antigen processing (TAP) system (TC# 3.A.1.209.1), and it's 3-D structure has been determined (Karska et al. 2019).  UL49.5 contains an extracellular region (residues 1-35) and a transmembrane-intracellular segment (residues 36-75), with a flexible membrane-proximal helical structure in the extracellular part, two short alpha-helices in the transmembrane region, and an unordered structure for the cytoplasmic part. Karska et al. 2019 propose three different orientations of UL49.5 when in complex with TAP.

Viruses
Herpesvirales
GN of Bovine herpes virus
*8.B.25.1.3









GN1 of 95 aas and 2 TM

Viruses
Herpesvirales
GN1 of Feline herpesvirus 1 (FeHV-1) (Feline viral rhinotracheitis virus)
*8.B.25.1.4









GN1 or UL49.5 of 87 aas and 2 TMSs.  May be N-terminally truncated.

Viruses
Herpesvirales
GN1 of Human herpesvirus 3 (HHV-3) (Varicella-zoster virus)
*8.B.25.1.5









UL49.5 of 95 aas and 2 TMSs

Viruses
Herpesvirales
UL49.5 of Gallid herpesvirus 3
*8.B.25.1.6









Human herpes virus GN1 of 91 aas

Viruses
Herpesvirales
GN1 of Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1)
*8.B.25.1.7









UL49.5 of 97 aas and 2 TMSs

Viruses
Herpesvirales
UL49.5 of Leporid herpesvirus 4
*8.B.25.1.8









Glycoprotein N of 78 aas and 2 TMSs

Viruses
Herpesvirales
GN of Cercopithecine herpesvirus 16 (CeHV-16) (Herpesvirus papio 2)
*8.B.25.2.1









BLRF1 or GN of 102 aas and 2 TMSs

Viruses
Herpesvirales
BLRF1 of Epstein-Barr virus (HHV-4) (Human herpesvirus 4)
*8.B.25.2.2









Envelope glycoprotein N, UL73, of 104 aas and 2 TMSs

Viruses
Herpesvirales
UL73 of Simian cytomegalovirus
*8.B.25.2.3









gpUL73 of 134 aas and 2 TMSs

Viruses
Herpesvirales
gpUL73 of Human cytomegalovirus (HHV-5) (Human herpesvirus 5)