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8.B.28.1.1
Mu-conotoxin (Mu-conopeptide) SIIIA of 73 aas.  Inhibits both Na+ and K+ channels specifically; thus Kv1.1 and Kv1.6 are inhibited, but other K+ channels tested were not (Leipold et al. 2016).  Of Na+ channels, this toxin moderately blocks rNav1.1/SCN1A, rNav1.2/SCN2A, rNav1.3/SCN3A, rNav1.4/SCN4A, and mNav1.6/SCN8A (Wang et al. 2006; Yao et al. 2008; Bulaj et al. 2005).

Accession Number:Q86DU6
Protein Name:Mu-conotoxin SIIIA
Length:73
Molecular Weight:8105.00
Species:Conus striatus (Striated cone) [6493]
Location1 / Topology2 / Orientation3: Secreted1
Substrate NONE

Cross database links:

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  • 2° Structure (Network Protein Sequence Analysis)

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FASTA formatted sequence
1:	MMSKLGVLLT VCPLLFPLTA LPPDGDQPAD RPAERMQDDI SSDEHPLFDK RQNCCNGGCS 
61:	SKWCRDHARC CGR