TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*8.B.4.1.1









Conotoxin, 33 aas
Eukaryota
Metazoa
Conotoxin of Conus ventricosus (cone snail) (P83301)
*8.B.4.1.2









Conotoxin scaffold VI/VII precursor (CSP), 79 aas
Eukaryota
Metazoa
CSP of Conus pennaceus (AAG60403)
*8.B.4.1.3









Conopeptide precursor of 82 aas and 1 TMS.

Eukaryota
Metazoa
Conopeptide precursor of Conus marmoreus (marble cone)
*8.B.4.1.4









O-superfamily conotoxin of 73 aas

Eukaryota
Metazoa
Conus toxin of Conus ebraeus
*8.B.4.1.5









Huwentoxin-X or Ω-theraphotoxin-Hh1a of 68 aas.  Voltage-gated Ca2+ channel blocker.  The 3-d solution structure is known (Liu et al. 2006).

Eukaryota
Metazoa
Hwentoxin-X of Haplopelma schmidti (Selenocosmia huwena)
*8.B.4.1.6









U4-therophotoxin-Cj1a of 74 aas

Eukaryota
Metazoa
Therophotoxin of Chilobrachys guangxiensis (Chinese earth tiger tarantula) (Chilobrachys jingzhao)
*8.B.4.1.7









δ-conotoxin, TxVIA of 78 aas and 1 TMS.  Binds to the extracellular sides of voltage-gated sodium channels (Nav) and inhibits the inactivation process. Binding of this toxin is calcium-dependent but not voltage-dependent.  It is important in mollusks for the paralysis of prey.  The 3-d solution structure is known (Kohno et al. 2002).

Eukaryota
Metazoa
Conotoxin of Conus textile (Cloth-of-gold cone)
*8.B.4.2.1









T-2 (Chi) Conotoxin MrIA precursor (61aas) (inhibitor of the human norepinephrine transporter) (Lovelace et al., 2006).

Eukaryota
Metazoa
MrIA of Conus marmoreus (P58808)
*8.B.4.3.1









Conotoxin Ca5.1 precursor (71 aas) (Peng et al., 2007)

Eukaryota
Metazoa
Conotoxin Ca5.1 precursor of Conus caracteristicus (P0C666)