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8.B.5.2.2
κ-Sparatoxin-Hv1b or heteropodatoxin 2 of 30 aas;  Inhibitor of voltage-gated potassium channels of the Kv4/KCND family (Ramracheya et al. 2010). Inhibition of Kv4.3/KCND3 and Kv4.2/KCND2 is strongly voltage-dependent, while inhibition of Kv4.1/KCND1 shows less voltage-dependence. Its binding site may be near the potassium channel voltage sensor. Also blocks calcium channels.

Accession Number:P58426
Protein Name:Kappa-sparatoxin-Hv1b
Length:30
Molecular Weight:3420.00
Species:Heteropoda venatoria (Brown huntsman spider) [152925]
Location1 / Topology2 / Orientation3: Secreted1
Substrate NONE

Cross database links:

Structure:
1EMX     

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	DDCGKLFSGC DTNADCCEGY VCRLWCKLDW