TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


8.B.5.3.2
Vanillotoxin-3 (VaTx3) (34 aas; 50% identical to VATx1) (activates TRPV1 causing pain) (Cramer and McIntyre, 2008)

Accession Number:P0C246
Protein Name:VaTx3
Length:34
Molecular Weight:4190.00
Species:Psalmopoeus cambridgei (Trinidad chevron tarantula) [179874]
Location1 / Topology2 / Orientation3: Secreted1
Substrate NONE

Cross database links:

Pfam: PF07740   

Gene Ontology

GO:0005576 C:extracellular region
GO:0019870 F:potassium channel inhibitor activity
GO:0009405 P:pathogenesis

References (1)

[1] “Spider toxins activate the capsaicin receptor to produce inflammatory pain.”  Siemens J.et.al.   17093448

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	ECRWYLGGCK EDSECCEHLQ CHSYWEWCLW DGSF