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8.B.6.1.2
Mu-agatoxin II (37aas)

Accession Number:P11058
Protein Name:Mu-agatoxin-Aa1b
Length:37
Molecular Weight:4110.00
Species:agelenopsis aperta (North American funnel-web spider) [6908]
Location1 / Topology2 / Orientation3: Secreted1
Substrate NONE

Cross database links:

Pfam: PF05980   

Gene Ontology

GO:0005576 C:extracellular region
GO:0042734 C:presynaptic membrane
GO:0019871 F:sodium channel inhibitor activity
GO:0009405 P:pathogenesis
GO:0007268 P:synaptic transmission

References (2)

[1] “Purification and characterization of two classes of neurotoxins from the funnel web spider, Agelenopsis aperta.”  Skinner W.S.et.al.   2914898
[2] “Agatoxins: ion channel specific toxins from the American funnel web spider, Agelenopsis aperta.”  Adams M.E.et.al.   15066410

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	ECATKNKRCA DWAGPWCCDG LYCSCRSYPG CMCRPSS