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8.B.6.1.8
Tachystatin-B1 of 42 aas.  Exhibits stronger antimicrobial activity against Gram-positive bacteria (S. aureus  (IC50 is 7.4 µg/ml)), fungi (C. albicans (IC50 is 3.0 µg/ml) and P. pastoris (IC50 is 0.1 µg/ml)) than Gram-negative bacteria (E.coli, no inhibition at 100 µg/ml). Binds to chitin. Does not cause hemolysis on sheep erythrocytes. Has no blocking activity on the P-type calcium channel.

Accession Number:P0C1Z8
Protein Name:Tachystatin-B1
Length:42
Molecular Weight:4919.00
Species:Tachypleus tridentatus (Japanese horseshoe crab) [6853]
Location1 / Topology2 / Orientation3: Secreted1
Substrate NONE

Cross database links:

Structure:
2DCV     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
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  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	YVSCLFRGAR CRVYSGRSCC FGYYCRRDFP GSIFGTCSRR NF