TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*8.B.6.1.1









Ω-agatoxin IVA

Eukaryota
Metazoa
Ω-agatoxin IVA of Agelenopsis aperta (P30288)
*8.B.6.1.2









Mu-agatoxin II (37aas)

Eukaryota
Metazoa
Mu-agatoxin II of Agelenopsis aperta (P11058)
*8.B.6.1.3









Mu-agatoxin-Hc1a (Curtatoxin-1) (36aas)

Eukaryota
Metazoa
Curtatoxin-1 of Hololena curta (P15967)
*8.B.6.1.4









U10-Ctenitoxin-Co1a of 37 aas (Trachsel et al. 2012).

Eukaryota
Metazoa
Ctentitoxin of Ctenus ornatus (Oligoctenus ornatus; brazilian spider)

 
*8.B.6.1.5









Putative toxin of 148 aas

Eukaryota
Metazoa
Putative toxin of Tribolium castaneum (red flour beetle)
*8.B.6.1.6









U3-Agatoxin Ao1h of 69 aas

Eukaryota
Metazoa
Agatoxin of Agelena orientalis
*8.B.6.1.7









U2-agatoxin Ao1k of 69 aas.  Insect active toxin causing rapid but reversible paralysis in crickets. No activity shown in mammals. Does not show effect on mammalian voltage-gated calcium channels.

Eukaryota
Metazoa
Agatoxin of Agelena orientalis
*8.B.6.1.8









Tachystatin-B1 of 42 aas.  Exhibits stronger antimicrobial activity against Gram-positive bacteria (S. aureus  (IC50 is 7.4 µg/ml)), fungi (C. albicans (IC50 is 3.0 µg/ml) and P. pastoris (IC50 is 0.1 µg/ml)) than Gram-negative bacteria (E.coli, no inhibition at 100 µg/ml). Binds to chitin. Does not cause hemolysis on sheep erythrocytes. Has no blocking activity on the P-type calcium channel.

Eukaryota
Metazoa
Tachystatin of Tachypleus tridentatus (Japanese horseshoe crab)
*8.B.6.2.1









Delta atracotoxin-Hv1a (Versutoxin) (42aas) (NMR structure available (1VTXA)). Antagonist of insect voltage-gated calcium channels (Chong et al., 2007; Khan et al., 2006; Wang et al., 1999) as well as sodium channels (Luch 2010).

Eukaryota
Metazoa
Versutoxin of Hadronyche versuta (P13494)
*8.B.6.2.2









Delta hexatoxin-Mg1a; Neurotoxin Magi-4 (105aas).  Targets sites 3 and 4 of mammalian Na+ channels; slows inactivation (Yamaji et al., 2009).

Eukaryota
Metazoa
Neurotoxin Magi-4 of Macrothele gigas (P83560)