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9.A.18.1.1
Microcin uptake permease, SbmA

Accession Number:P0AFY6
Protein Name:Protein SbmA aka B0377
Length:406
Molecular Weight:46459.00
Species:Escherichia coli [83333]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Microcin

Cross database links:

Genevestigator: P0AFY6
EchoBASE: EB0921
EcoGene: EG10928
eggNOG: COG1133
HEGENOM: HBG289932
RefSeq: AP_001028.1    NP_414911.1   
Entrez Gene ID: 946884   
Pfam: PF05992   
BioCyc: EcoCyc:SBMA-MONOMER    ECOL168927:B0377-MONOMER   
KEGG: ecj:JW0368    eco:b0377   

Gene Ontology

GO:0009276 C:Gram-negative-bacterium-type cell wall
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0055085 P:transmembrane transport

References (4)

[1] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[2] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[3] “Identification, mapping, cloning and characterization of a gene (sbmA) required for microcin B17 action on Escherichia coli K12.”  Lavina M.et.al.   3543211
[4] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MFKSFFPKPG TFFLSAFVWA LIAVIFWQAG GGDWVARITG ASGQIPISAA RFWSLDFLIF 
61:	YAYYIVCVGL FALFWFIYSP HRWQYWSILG TALIIFVTWF LVEVGVAVNA WYAPFYDLIQ 
121:	TALSSPHKVT IEQFYREVGV FLGIALIAVV ISVLNNFFVS HYVFRWRTAM NEYYMANWQQ 
181:	LRHIEGAAQR VQEDTMRFAS TLENMGVSFI NAIMTLIAFL PVLVTLSAHV PELPIIGHIP 
241:	YGLVIAAIVW SLMGTGLLAV VGIKLPGLEF KNQRVEAAYR KELVYGEDDA TRATPPTVRE 
301:	LFSAVRKNYF RLYFHYMYFN IARILYLQVD NVFGLFLLFP SIVAGTITLG LMTQITNVFG 
361:	QVRGAFQYLI NSWTTLVELM SIYKRLRSFE HELDGDKIQE VTHTLS