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9.A.26.1.1
The 7-amino cholesterol resistance protein, Rta1p

Accession Number:P53047
Protein Name:Rta1p
Length:317
Molecular Weight:35486.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate 7-amino cholesterol

Cross database links:

Genevestigator: P53047
eggNOG: fuNOG10056
HEGENOM: HBG447992
DIP: DIP-1599N
RefSeq: NP_011729.1   
Entrez Gene ID: 853127   
Pfam: PF04479   
KEGG: sce:YGR213C   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0006950 P:response to stress

References (4)

[1] “Characterization of the Saccharomyces cerevisiae RTA1 gene involved in 7-aminocholesterol resistance.”  Soustre I.et.al.   8660468
[2] “Sequence analysis of 203 kilobases from Saccharomyces cerevisiae chromosome VII.”  Rieger M.et.al.   9290212
[3] “The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.”  Tettelin H.et.al.   9169869
[4] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAKDGFELYR YTPELGASIL FTVLFAVSGV AFVILLFHYS VKSKRRVGSL MKSQPVLRYY 
61:	GTVNLAGAYI PFIFGCFVEC VGFAFRCKSS KDTTLLNPYI IQTVFLLVSP TLYAASIYMI 
121:	FGRMATLLFA ENLMIMPARF NTTIFVIGDV GSLLLQAIGG AMMSKVTSAS SGSHLVTAGL 
181:	FIQIAFFGLF IINEVLFIFK MSKKPTNVSV RYGSWKYLNI ALLVNSFLIL IRSIVRAVEF 
241:	IQGYDGEIAS HEWYLYIFDG LPMFLLVLIF IVAFPLINIF RIHEESIQAQ QSARFDGTDY 
301:	PDVEVTSIEE DLASKSE