TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*9.A.29.1.1









LanG is a Lantibiotic immunity protein. It may or may not function with LanEF ( an ABC antibiotic exporter; TC 3.A.1.131.2) (Okuda et al., 2010). The 6 TMSs of LanG show sequence similarity with TMSs 6-10 of DME family proteins (see 2.A.7.3.17).

 

Bacteria
Firmicutes
LanG of Bacillus licheniformis (A5A639)
*9.A.29.2.1









Uncharacterized protein of 445 aas and 11 TMSs

Bacteria
Bacteroidetes/Chlorobi group
UP of Bacteroides sp.
*9.A.29.3.1









Uncharacterized protein of 441 aas and 11 TMSs.

Eukaryota
Fungi
UP of Schizosaccharomyces pombe (Fission yeast)
*9.A.29.3.2









Uncharacterized protein of 528 aas and 8 TMSs in a 6 + 2 arrangement.

Eukaryota
Viridiplantae
UP of Arabidopsis thaliana (Mouse-ear cress)
*9.A.29.3.3









Serine incorporator of 708 aas and 7 - 9 TMSs.

Eukaryota
Metazoa
Serine incorporator of Clonorchis sinensis (Chinese liver fluke)
*9.A.29.3.4









Serine incorporator 3 of 473 aas and 11 TMSs. May exhibit L-serine transmembrane transport activity.  Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm (Usami et al. 2015).

Eukaryota
Metazoa
Serinc3 of Homo sapiens