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9.A.36.1.4
Phospholipid scramblase 4, PLS4, PLSCR4 or GIG43 of 329 aas.  Accelerates ATP-independent bidirectional transbilayer flipping of phospholipids upon binding calcium ions. Results in loss of phospholipid asymmetry in the plasma membrane (Vinnakota and Gummadi 2016).

Accession Number:Q9NRQ2
Protein Name:Phospholipid scramblase 4
Length:329
Molecular Weight:37005.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Membrane1 / Single-pass type II membrane protein2
Substrate phospholipids

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSGVVPTAPE QPAGEMENQT KPPDPRPDAP PEYNSHFLPG PPGTAVPPPT GYPGGLPMGY 
61:	YSPQQPSTFP LYQPVGGIHP VRYQPGKYPM PNQSVPITWM PGPTPMANCP PGLEYLVQLD 
121:	NIHVLQHFEP LEMMTCFETN NRYDIKNNSD QMVYIVTEDT DDFTRNAYRT LRPFVLRVTD 
181:	CMGREIMTMQ RPFRCTCCCF CCPSARQELE VQCPPGVTIG FVAEHWNLCR AVYSIQNEKK 
241:	ENVMRVRGPC STYGCGSDSV FEVKSLDGIS NIGSIIRKWN GLLSAMADAD HFDIHFPLDL 
301:	DVKMKAMIFG ACFLIDFMYF ERSPPQRSR