TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*9.A.43.1.1









Cd2+ tolerance factor, TaTM20, a hydrophobic polypeptide of 889 amino acids, containing 20 transmembrane domains arranged as a 5-fold internal repeating unit of 4 transmembrane domains each (Kim et al., 2008).  The 4 TMS repeat has been referred to as the pfam13962 or PGG domain.  The PGG domain is named for the conserved sequence motif found at the start of the domain.The protein appears to function as a Cd2+ exporter, possibly using the pmf and functioning as a secondary carrier (see family description).

Eukaryota
Viridiplantae
Cd2+ tolerance factor of Triticum aestivum (Q2MJU2)
*9.A.43.1.2









Uncharacterized protein of 175 aas and 4 TMSs.

Eukaryota
Viridiplantae
UP of Glycine max (Soybean) (Glycine hispida)
*9.A.43.1.3









Uncharacterized protein of 459 aas and 4 C-terminal TMSs.

Eukaryota
Viridiplantae
UP of Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
*9.A.43.1.4









Uncharacterized protein of 179 aas and 4 TMSs.

Eukaryota
Viridiplantae
UP of Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa)
*9.A.43.1.5









Embryogeneis transmembrane protein of 275 aas and 4 TMSs

Eukaryota
Viridiplantae
E-TMP of Zea mays (Maize)
*9.A.43.1.6









Embryogenesis transmembrane protein of 1276 aas and 20 TMSs, E-TMP or TM20. It is present in differentiating provascular cells in rice and maize embryos, and has a polarized distribution within the cell in the more differentiated stages of development, and modifieds transport properties when injected into frog oocytes (Jahrmann et al. 2005).

 

Eukaryota
Viridiplantae
E-TMP of Oryza sativa subsp. japonica (Rice)
*9.A.43.1.7









Embryogenesis transmembrane protein of 275 aas and 6 TMSs

Eukaryota
Viridiplantae
E-TMP of Oryza sativa subsp. japonica (Rice)
*9.A.43.1.8









Uncharacterized protein of 227 aas and 5 TMSs.

Eukaryota
Viridiplantae
UP of Triticum urartu (Red wild einkorn) (Crithodium urartu)
*9.A.43.1.9









Embryogenesis transmembrane protein Dek34 or TM20 of 1,389 aas and 21 TMSs in a 1 + 4 + 4 + 4 + 4 + 4 TMS arrangement, where each 4 TMS repeat unit has a 1 + 3 TMS arrangement.  TM20 is present in differentiating provascular cells in maize embryos. The protein has a polarized distribution within the cell in the more differentiated stages of development. Xenopus laevis oocytes microinjected with TM20 appear to show modified transport activities across the plasma membrane (Jahrmann et al. 2005).

Eukaryota
Viridiplantae
TM20 of Zea mays (Maize)
*9.A.43.1.10









Uncharacterized protein of 464 aas and 4 C-terminal TMSs (residues 300 - 450). The N-terminal domain is an ankyrin domain, showing extensive similarity to members of TC families 1.A.4 (TRP-CC) and 8.A.28 (Ankyrin domain proteins).  The C-terminal TMSs are in a 1 + 3 TMS arrangement as is true of other members of the TC# 9.A.43 (CTEP) family.

Eukaryota
Viridiplantae
UP of Acer yangbiense
*9.A.43.1.11









Uncharacterized protein of 219 aas and 4 C-terminal TMSs.

Eukaryota
Viridiplantae
UP of Panicum miliaceum
*9.A.43.1.12









Uncharacterized ankyrin repeat family protein of 574 aas and 4 C-terminal TMSs.  Other TMSs may be present in the large N-terminal ankyrin domain. This protein, and many others, share domains with 9.A.43 and 8.A.28, due to the ankyrin domains.

Eukaryota
Viridiplantae
Ankyrin repeat protein of Arabidopsis thaliana
*9.A.43.1.13









Uncharacterized protein of 222 aas and 4 C-terminal TMSs.

Eukaryota
Viridiplantae
UP of Brachypodium distachyon
*9.A.43.1.14









The accelerated cell death 6, ACD6, of 670 aas and 5 C-terminal TMSs. It is an activator of the defense response against virulent pathogens, including bacteria, fungi and oomycetes, that acts in a positive feedback loop with the defense signal salicylic acid (SA) (Lu et al. 2009).It regulates the salicylic acid (SA) signaling pathway leading to cell death and modulating cell fate (e.g. cell enlargement and/or cell division) (Lu et al. 2003). In response to SA signaling, it triggers the accumulation of FLS2 at the plasma membrane, thus priming defenses (Zhang et al. 2014). Irt it is involved in SA-dependent freezing signaling and tolerance (Miura and Ohta 2010). Information exchange between the ankyrin and transmembrane domains may be involved in activating defense signaling (Lu et al. 2005).

 


Eukaryota
Viridiplantae
ACD6 of Arabidopsis thaliana
*9.A.43.1.15









Uncharacterized ankyrin domain-containing protein of 210 aas and 4 TMSs.  Overlapping regions of homology with other members of this family as well as with TC# 9.B.257 seems likely but have not been demonstrated.

Eukaryota
Viridiplantae
UP of Arachis duranensis