9.A.45 The Archaeocin/Halocin C8 (HalC8) Family
Archaeocins are ribosomally-synthesized antimicrobial peptides or proteins produced by Archaea. Halocins and sulfolobicins are produced by archaea belonging to the order Halobacteriales (Euryarchaeota) and Sulfolobales (Crenarchaeota), respectively. These weapons contribute towards helping the producer to prosper in spite of the microbial warfare. HalC8, when applied to a target cell, causes cell swelling followed by lysis (Besse et al. 2015).