TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*9.A.46.1.1









Tetraspanning Clarin-1, CLRN1 (USH3A gene).  The causative protein which when mutated, gives rise to human Usher syndrome type 3A (Phillips et al. 2013), blind-deafness (Reiners et al. 2006).  It exists in the USH complex involved in mechano-transduction in auditory hair cells and phooreceptors (Zallocchi et al. 2009; Ogun and Zallocchi 2014).

Eukaryota
Metazoa
Clarin-1 of Homo sapiens (P58418)
*9.A.46.1.2









Tetraspanning Clarin-2

Eukaryota
Metazoa
Clarin-2 of Homo sapiens (A0PK11)
*9.A.46.1.3









Tetraspanning Clarin-3

Eukaryota
Metazoa
Clarin-3 of Homo sapiens (Q8NCR9)
*9.A.46.1.4









Clarin-1 (Clrn1) of 232 aas and 4 TMSs.  Present in hair cells and photreceptors where it's defect causes hearing and visual loss (Usher syndrome type 3 in humans) (Ogun and Zallocchi 2014).

Eukaryota
Metazoa
Clarin-1 of Danio rerio (Zebrafish) (Brachydanio rerio)
*9.A.46.2.1









Sea anemone clarin homologue

Eukaryota
Metazoa
Clarin homologue of Nematostella vectensis (A7SGP9)
*9.A.46.2.2









Uncharacterized protein of 224 aas and 4 TMSs.

Eukaryota
Metazoa
UP of Necator americanus (Human hookworm)
*9.A.46.2.3









Fly clarin homologue, CG1103 isoform A

Eukaryota
Metazoa
Clarin homologue of Drosophila melanogaster (Q960K3)
*9.A.46.2.4









Uncharacterized protein of 225 aas and 4 TMSs

Eukaryota
Metazoa
UP of Acyrthosiphon pisum (Pea aphid)
*9.A.46.2.5









Uncharacterized protein of 236 aas and 4 TMSs.

Eukaryota
Metazoa
UP of Lottia gigantea (Giant owl limpet)