TCDB is operated by the Saier Lab Bioinformatics Group

9.B.116 The Transporter, YvqF (YvqF) Family

The YvqF family includes thousands of sequenced proteins, all of which have an N-terminal transmembrane domain of probably of 2-4 TMSs (residues 1-~120) plus a C-terminal hydrophilic Duf2154 domain that includes a central semihydrophobic region of about 50 residues that is sometimes predicted to comprise an additional 2 TMSs. An example is YvqF of Streptococcus dysgalactiae (9.B.110.1.1). The Duf2154 domain may contain an internal repeat of about 44 aas. The function is unknown.