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9.B.12.3.1
Uncharacterized ORF, Sna3 (YJL151c).  Targeting to the endosomal pathway depends on its interaction with Rsp5p, and multivesicular body sorting depends on ubiquitylation (Stawiecka-Mirota et al. 2007).

Accession Number:P14359
Protein Name:YJP1 aka YJL151c aka J0630
Length:133
Molecular Weight:15199.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P14359
eggNOG: KOG1773
DIP: DIP-1730N
RefSeq: NP_012384.1   
Entrez Gene ID: 853290   
Pfam: PF01679   
KEGG: sce:YJL151C   

Gene Ontology

GO:0030659 C:cytoplasmic vesicle membrane
GO:0000328 C:fungal-type vacuole lumen
GO:0016021 C:integral to membrane
GO:0031902 C:late endosome membrane
GO:0042802 F:identical protein binding

References (10)

[1] “Biosynthesis of inositol in yeast. Primary structure of myo-inositol-1-phosphate synthase (EC 5.5.1.4) and functional analysis of its structural gene, the INO1 locus.”  Dean-Johnson M.et.al.   2642902
[2] “Sequence analysis of a 40.7 kb segment from the left arm of yeast chromosome X reveals 14 known genes and 13 new open reading frames including homologues of genes clustered on the right arm of chromosome XI.”  Katsoulou C.et.al.   8813765
[3] “Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.”  Galibert F.et.al.   8641269
[4] “Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.”  Hu Y.et.al.   17322287
[5] “Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting.”  Reggiori F.et.al.   11566881
[6] “Global analysis of protein localization in budding yeast.”  Huh W.-K.et.al.   14562095
[7] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[8] “A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery.”  Hitchcock A.L.et.al.   14557538
[9] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258
[10] “Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.”  Smolka M.B.et.al.   17563356
Structure:
4LCD     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDRDHINDHD HRMSYSINKD DLLLMVLAVF IPPVAVWKRK GMFNRDTLLN LLLFLLLFFP 
61:	AIIHACYVVY ETSSERSYDL SRRHATAPAV DRDLEAHPAE ESQAQPPAYD EDDEAGADVP 
121:	LMDNKQQLSS GRT