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9.B.125.1.1
AmpE (284aas; 6 putative TMSs). Putative signal transduction protein for ampicillin resistance. 

Accession Number:P0AE14
Protein Name:Protein AmpE
Length:284
Molecular Weight:32122.00
Species:Escherichia coli (strain K12) [83333]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P0AE14
EchoBASE: EB0040
EcoGene: EG10042
eggNOG: COG3725
HEGENOM: HOG000116788
DIP: DIP-47964N
Entrez Gene ID: 946678   
KEGG: eco:b0111   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

References (5)

[1] “Signalling proteins in enterobacterial AmpC beta-lactamase regulation.”  Lindquist S.et.al.   2691840
[2] “Regulation of enterobacterial cephalosporinase production: the role of a membrane-bound sensory transducer.”  Honore N.et.al.   2607970
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTLFTTLLVL IFERLFKLGE HWQLDHRLEA FFRRVKHFSL GRTLGMTIIA MGVTFLLLRA 
61:	LQGVLFNVPT LLVWLLIGLL CIGAGKVRLH YHAYLTAASR NDSHARATMA GELTMIHGVP 
121:	AGCDEREYLR ELQNALLWIN FRFYLAPLFW LIVGGTWGPV TLMGYAFLRA WQYWLARYQT 
181:	PHHRLQSGID AVLHVLDWVP VRLAGVVYAL IGHGEKALPA WFASLGDFHT SQYQVLTRLA 
241:	QFSLAREPHV DKVETPKAAV SMAKKTSFVV VVVIALLTIY GALV