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9.B.125.2.2
CbiB/CobD family protein. (328aas; 6 TMSs).

Accession Number:Q8PVB2
Protein Name:Probable cobalamin biosynthesis protein CobD
Length:328
Molecular Weight:35723.00
Species:Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) [192952]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

eggNOG: COG1270
HEGENOM: HOG000290070
Entrez Gene ID: 1480401   
Pfam: PF03186   
KEGG: mma:MM_2059   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015420 F:cobalamin-transporting ATPase activity
GO:0009236 P:cobalamin biosynthetic process

References (1)

[1] “The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea.”  Deppenmeier U.et.al.   12125824

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MIIPDSGHLA LVLLLAAVID IVFGEPPAAV HPVVWIGKLI SFLKNAAPKN HRKLYGTAMA 
61:	LFCVLFASLL GYSVLYIAAL PGIPGFLALL IEAYFLKATF AINCLLSPAR EIYKHLEENR 
121:	LEKVRELLPI YVSRNTSKLT KNQMSSAVVE SVSENYVDGI LSPIFYYAVF GEYGLVAAYA 
181:	FKAISTLDSM VGYKTEPYKE LGYFSAKSDD VLNWIPARIS VIFILAAAFT VSLFPKKGRK 
241:	INPFDSVKTA LKDGMKTPSP NSGYPMAATA GALGVKLEKP NTYVLGASYP PTEIKDIKRV 
301:	SQLIAIASGF SLVAFVAVIR MAGIYLHP