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9.B.186 The Putative Lipoprotein Supressor of a ts bamD mutant, YiaD (YiaD) Family

Tachikawa and Kato 2011 isolated temperature-sensitive mutants of the E. coli bamD gene, which is essential for the assembly of β-barrel outer membrane proteins. As their multicopy suppressor, they identified a novel yiaD gene encoding a putative lipoprotein, YiaD with 3 putative N-terminal TMSs and a C-terminal peptidoglycan-binding domain. Mutations of its OmpA domain, which is required for interaction with peptidoglycan, affected suppression, suggesting that interaction with peptidoglycan is important for YiaD function.

References associated with 9.B.186 family:

Tachikawa, T. and J. Kato. (2011). Suppression of the temperature-sensitive mutation of the bamD gene required for the assembly of outer membrane proteins by multicopy of the yiaD gene in Escherichia coli. Biosci. Biotechnol. Biochem. 75: 162-164. 21228468