TCDB is operated by the Saier Lab Bioinformatics Group

9.B.189 The Vesicular Membrane Neurensin (Neurensin) Family 

Nuerensins may play important roles in neural organelle transport, transduction of nerve signals and  nerve growth. May also play a role in neurite extension.

References associated with 9.B.189 family:

Boada-Romero, E., I. Serramito-Gómez, M.P. Sacristán, D.L. Boone, R.J. Xavier, and F.X. Pimentel-Muiños. (2016). The T300A Crohn''s disease risk polymorphism impairs function of the WD40 domain of ATG16L1. Nat Commun 7: 11821. 27273576
Dupont, N., A.C. Nascimbeni, E. Morel, and P. Codogno. (2017). Molecular Mechanisms of Noncanonical Autophagy. Int Rev Cell Mol Biol 328: 1-23. 28069131
Hurley, J.H. and L.N. Young. (2017). Mechanisms of Autophagy Initiation. Annu. Rev. Biochem. 86: 225-244. 28301741
Keremu, A., X. Maimaiti, A. Aimaiti, M. Yushan, Y. Alike, Y. Yilihamu, and A. Yusufu. (2017). NRSN2 promotes osteosarcoma cell proliferation and growth through PI3K/Akt/MTOR and Wnt/β-catenin signaling. Am J Cancer Res 7: 565-573. 28401012
Molino, D., N. Zemirli, P. Codogno, and E. Morel. (2017). The Journey of the Autophagosome through Mammalian Cell Organelles and Membranes. J. Mol. Biol. 429: 497-514. 27986571
Nagata, K., H. Suzuki, A. Niiya-Kato, S. Kinoshita, S. Taketani, and M. Araki. (2006). Neurensin-1 expression in the mouse retina during postnatal development and in the cultured retinal neurons. Brain Res 1081: 65-71. 16696124
Nakanishi, K., M. Ida, H. Suzuki, C. Kitano, A. Yamamoto, N. Mori, M. Araki, and S. Taketani. (2006). Molecular characterization of a transport vesicle protein Neurensin-2, a homologue of Neurensin-1, expressed in neural cells. Brain Res 1081: 1-8. 16527258
Song, S., J. Tan, Y. Miao, M. Li, and Q. Zhang. (2017). Crosstalk of autophagy and apoptosis: Involvement of the dual role of autophagy under ER stress. J Cell Physiol 232: 2977-2984. 28067409
Sun, Y., Y. Chen, J. Zhang, L. Cao, M. He, X. Liu, N. Zhao, A. Yin, H. Huang, and L. Wang. (2017). TMEM74 promotes tumor cell survival by inducing autophagy via interactions with ATG16L1 and ATG9A. Cell Death Dis 8: e3031. 29048433
Tang, W., A. Ren, H. Xiao, H. Sun, and B. Li. (2017). Highly expressed NRSN2 is related to malignant phenotype in ovarian cancer. Biomed Pharmacother 85: 248-255. 27908706
Wu, D.J. and I.E. Adamopoulos. (2017). Autophagy and autoimmunity. Clin Immunol 176: 55-62. 28095319
Yu, C., L. Wang, B. Lv, Y. Lu, L. Zeng, Y. Chen, D. Ma, T. Shi, and L. Wang. (2008). TMEM74, a lysosome and autophagosome protein, regulates autophagy. Biochem. Biophys. Res. Commun. 369: 622-629. 18294959
Zhang, X.Y., J.L. Kuang, C.S. Yan, X.Y. Tu, J.H. Zhao, X.S. Cheng, and X.Q. Ye. (2015). NRSN2 promotes non-small cell lung cancer cell growth through PI3K/Akt/mTOR pathway. Int J Clin Exp Pathol 8: 2574-2581. 26045763