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9.B.20.1.2
Putative Mg2+ transporter, virulence factor, MgtC.  The C-terminal domain is a divergent ACT domain (Yang et al. 2012).  The claim that MgtC is a Mg2+ transporter has been refuted (Yang et al. 2012).

Accession Number:O07221
Protein Name:MgtC aka RV1811 aka MTCY16F9.03C aka MT1859
Length:234
Molecular Weight:24807.00
Species:Mycobacterium tuberculosis [1773]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Mg2+

Cross database links:

HEGENOM: HBG708751
RefSeq: NP_216327.1    NP_336318.1   
Entrez Gene ID: 885439    923776   
Pfam: PF02308   
KEGG: mtc:MT1859    mtu:Rv1811   

Gene Ontology

GO:0016020 C:membrane
GO:0004012 F:phospholipid-translocating ATPase activity

References (2)

[1] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.”  Cole S.T.et.al.   9634230
[2] “Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.”  Fleischmann R.D.et.al.   12218036
Structure:
2LQJ     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MQTLTVADFA LRLAVGVGCG AIIGLERQWR ARMAGLRTNA LVATGATLFV LYAVATEDSS 
61:	PTRVASYVVS GIGFLGGGVI LREGFNVRGL NTAATLWCSA AVGVLAASGH LVFTLIGTGT 
121:	IVAVHLLGRP LGRLVDRDNA VEDEGLQPYQ VRVICRPKAE TYVRAHIVQR TSSNDITLRG 
181:	IRTGPAGDDN ITLTAHLLMV GHTPAKLERL VAELSLQPGV YAVHWYAGEH AQAE