TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*9.B.22.1.1









The Morphogenesis protein, MorC (Gallant et al., 2008).

Bacteria
Proteobacteria
MorC of Aggregatibacter actinomycetemcomitans (Q4JI69)
*9.B.22.1.2









Inner membrane autotransporter assembly factor TamB (YtfN). Part of the translocation and assembly module (TAM) autotransporter assembly complex, which functions together with TamA and Omp85, both in the outer membrane (TC#1.B.33) to translocate autotransporters across the outer membrane (Selkrig et al. 2012). TamB has a signal-anchor linkage to the inner membrane, beta-helical structure, conserved domain architecture and a C-terminal region that mimics outer membrane protein beta-strands (Heinz et al. 2015).  It may function in folding of the passe3nger domain while BamA-TamAB catalyze membrane β-domain insertion (M. Babu et al., manuscript in preparation).

Bacteria
Proteobacteria
TamB of E. coli
*9.B.22.1.3









Uncharacterized protein of 1471 aas with a single N-terminal TMS.

Bacteria
Proteobacteria
UP of Acidovorax avenae
*9.B.22.1.4









Uncharacterized protein of 1322 aas and 1 N-terminal TMS.

Bacteria
Proteobacteria
UP of Bdellovibrio bacteriovorus
*9.B.22.1.5









TamB of 1578 aas.  Functions with TamA (TC# 1.B.33.2.4).

Bacteria
Proteobacteria
TamB of Sagittula stellata
*9.B.22.1.6









TamB homologue of 1369 aas

Bacteria
Acidobacteria
TamB of Koribacter versatilis
*9.B.22.1.7









TamB homologue; DUF490 family member of 1726 aas

Bacteria
Bacteroidetes
TamB of Salinibacter ruber
*9.B.22.1.8









Uncharacterized DUF490 domain containing protein of 1461 aas.

Bacteria
Firmicutes
DUF490 protein of Dialister invisus
*9.B.22.1.9









TamB homologue of 1684 aas

Bacteria
Armatimonadetes
TamB of Chthonomonas calidirosea
*9.B.22.2.1









The AsmA protein of 617aas with 1 N-terminal α-TMS and 20 predicted β-strands.  Associates with the inner and the outer membrane, probably spanning the envelope.  It influences OMP and LPS insertion, but it is not know if these effects are direct or indirect (Deng and Misra 1996).   In Salmonella species, AsmA (Q8Z5G2) activates expression of the marRAB operon and attenuates virulence with poor epithelial invasion (Prieto et al. 2009).

Bacteria
Proteobacteria
AsmA of E. coli
*9.B.22.2.2









AsmA of 618 aas with 1 N-terminal α-TMS and 23 predicted transmembrane β-strands, presumably in a β-barrel.  Probably spans the inner and outer membranes.  In Salmonella species, AsmA (Q8Z5G2) activates expression of the marRAB operon and attenuates virulence with poor epithelial invasion (Prieto et al. 2009).

Bacteria
Proteobacteria
AsmA of Salmonella typhi