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9.B.22.2.1
The AsmA protein of 617aas with 1 N-terminal α-TMS and 20 predicted β-strands.  Associates with the inner and the outer membrane, probably spanning the envelope.  It influences OMP and LPS insertion, but it is not know if these effects are direct or indirect (Deng and Misra 1996).   In Salmonella species, AsmA (Q8Z5G2) activates expression of the marRAB operon and attenuates virulence with poor epithelial invasion (Prieto et al. 2009).

Accession Number:P28249
Protein Name:Protein AsmA
Length:617
Molecular Weight:68963.00
Species:Escherichia coli (strain K12) [83333]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Periplasm1
Substrate Unknown

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRRFLTTLMI LLVVLVAGLS ALVLLVNPND FRDYMVKQVA ARSGYQLQLD GPLRWHVWPQ 
61:	LSILSGRMSL TAQGASQPLV RADNMRLDVA LLPLLSHQLS VKQVMLKGAV IQLTPQTEAV 
121:	RSEDAPVAPR DNTLPDLSDD RGWSFDISSL KVADSVLVFQ HEDDEQVTIR NIRLQMEQDP 
181:	QHRGSFEFSG RVNRDQRDLT ISLNGTVDAS DYPHDLTAAI EQINWQLQGA DLPKQGIQGQ 
241:	GSFQAQWQES HKRLSFNQIS LTANDSTLSG QAQVTLTEKP EWQLRLQFPQ LNLDNLIPLN 
301:	ETANGENGAA QQGQSQSTLP RPVISSRIDE PAYQGLQGFT ADILLQASNV RWRGMNFTDV 
361:	ATQMTNKSGL LEITQLQGKL NGGQVSLPGT LDATSINPRI NFQPRLENVE IGTILKAFNY 
421:	PISLTGKMSL AGDFSGADID ADAFRHNWQG QAHVEMTDTR MEGMNFQQMI QQAVERNGGD 
481:	VKAAENFDNV TRLDRFTTDL TLKDGVVTLN DMQGQSPVLA LTGEGMLNLA DQTCDTQFDI 
541:	RVVGGWNGES KLIDFLKETP VPLRVYGNWQ QLNYSLQVDQ LLRKHLQDEA KRRLNDWAER 
601:	NKDSRNGKDV KKLLEKM