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9.B.27.1.1
The YdjX protein. While not individually essential, the eight E. coli DedA family proteins are collectively essential (Boughner and Doerrler 2012).

Accession Number:P76219
Protein Name:YDJX_ECOLI
Length:236
Molecular Weight:26058.00
Species:Escherichia coli [83333]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Selenite

Cross database links:

Genevestigator: P76219
EchoBASE: EB3756
EcoGene: EG14000
eggNOG: COG0398
HEGENOM: HBG467051
DIP: DIP-11779N
RefSeq: AP_002369.1    NP_416264.4   
Entrez Gene ID: 946250   
Pfam: PF09335   
BioCyc: EcoCyc:G6945-MONOMER    ECOL168927:B1750-MONOMER   
KEGG: ecj:JW1739    eco:b1750   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

References (3)

[1] “A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map.”  Aiba H.et.al.   9097039
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNAERKFLFA CLIFALVIYA IHAFGLFDLL TDLPHLQTLI RQSGFFGYSL YILLFIIATL 
61:	LLLPGSILVI AGGIVFGPLL GTLLSLIAAT LASSCSFLLA RWLGRDLLLK YVGHSNTFQA 
121:	IEKGIARNGI DFLILTRLIP LFPYNIQNYA YGLTTIAFWP YTLISALTTL PGIVIYTVMA 
181:	SDLANEGITL RFILQLCLAG LALFILVQLA KLYARHKHVD LSASRRSPLT HPKNEG