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9.B.27.1.2
The YdjZ protein.  While not individually essential, the eight E. coli DedA family proteins are collectively essential (Boughner and Doerrler 2012).

Accession Number:P76221
Protein Name:YDJZ_ECOLI
Length:235
Molecular Weight:26160.00
Species:Escherichia coli [83333]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Selenite

Cross database links:

Genevestigator: P76221
EchoBASE: EB3758
EcoGene: EG14002
eggNOG: COG0398
HEGENOM: HBG491708
RefSeq: AP_002371.1    NP_416266.1   
Entrez Gene ID: 946269   
Pfam: PF09335   
BioCyc: EcoCyc:G6947-MONOMER    ECOL168927:B1752-MONOMER   
KEGG: ecj:JW1741    eco:b1752   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

References (3)

[1] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[2] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[3] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MMMMQSRKIW YYRITLIILL FAMLLAWALL PGVHEFINRS VAAFAAVDQQ GIERFIQSYG 
61:	ALAAVVSFLL MILQAIAAPL PAFLITFANA SLFGAFWGGL LSWTSSMAGA ALCFFIARVM 
121:	GREVVEKLTG KTVLDSMDGF FTRYGKHTIL VCRLLPFVPF DPISYAAGLT SIRFRSFFIA 
181:	TGLGQLPATI VYSWAGSMLT GGTFWFVTGL FILFALTVVI FMAKKIWLER QKRNA