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9.B.4.1.1
The universal stress protein-B (UspB).  This protein, a member of the sigma S regulon, has been shown to facilitate RuvC resolvase function during DNA repair and is therefore not likely to be a transporter (Persson et al. 2010).

Accession Number:P0A8S5
Protein Name:UspB aka b3494 aka JW3461
Length:111
Molecular Weight:13027.00
Species:Escherichia coli [83333]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P0A8S5
EchoBASE: EB2143
EcoGene: EG12231
eggNOG: NOG05863
HEGENOM: HBG303496
RefSeq: AP_004299.1    NP_417951.1   
Entrez Gene ID: 948008   
Pfam: PF10625   
BioCyc: EcoCyc:EG12231-MONOMER    ECOL168927:B3494-MONOMER   
KEGG: ecj:JW3461    eco:b3494   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0006950 P:response to stress

References (5)

[1] “Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.”  Sofia H.J.et.al.   8041620
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “uspB, a new sigmaS-regulated gene in Escherichia coli which is required for stationary-phase resistance to ethanol.”  Farewell A.et.al.   9829921
[5] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MISTVALFWA LCVVCIVNMA RYFSSLRALL VVLRNCDPLL YQYVDGGGFF TSHGQPNKQV 
61:	RLVWYIYAQR YRDHHDDEFI RRCERVRRQF ILTSALCGLV VVSLIALMIW H