TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


9.B.67.2.1
O-antigen polymerase, Rfc

Accession Number:P37748
Protein Name:O-antigen polymerase
Length:388
Molecular Weight:44744.00
Species:Escherichia coli [83333]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P37748
EchoBASE: EB1925
EcoGene: EG11982
HEGENOM: HBG086530
RefSeq: AP_002635.1    NP_416539.1   
Entrez Gene ID: 945179   
BioCyc: EcoCyc:EG11982-MONOMER    ECOL168927:B2035-MONOMER   
KEGG: ecj:JW2020    eco:b2035   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0009103 P:lipopolysaccharide biosynthetic process

References (6)

[1] “Genetic analysis of the O-specific lipopolysaccharide biosynthesis region (rfb) of Escherichia coli K-12 W3110: identification of genes that confer group 6 specificity to Shigella flexneri serotypes Y and 4a.”  Yao Z.et.al.   7517390
[2] “Structure of the O antigen of Escherichia coli K-12 and the sequence of its rfb gene cluster.”  Stevenson G.et.al.   7517391
[3] “A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map.”  Itoh T.et.al.   9097040
[4] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[5] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[6] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MIYLVISVFL ITAFICLYLK KDIFYPAVCV NIIFALVLLG YEITSDIYAF QLNDATLIFL 
61:	LCNVLTFTLS CLLTESVLDL NIRKVNNAIY SIPSKKVHNV GLLVISFSMI YICMRLSNYQ 
121:	FGTSLLSYMN LIRDADVEDT SRNFSAYMQP IILTTFALFI WSKKFTNTKV SKTFTLLVFI 
181:	VFIFAIILNT GKQIVFMVII SYAFIVGVNR VKHYVYLITA VGVLFSLYML FLRGLPGGMA 
241:	YYLSMYLVSP IIAFQEFYFQ QVSNSASSHV FWFFERLMGL LTGGVSMSLH KEFVWVGLPT 
301:	NVYTAFSDYV YISAELSYLM MVIHGCISGV LWRLSRNYIS VKIFYSYFIY TFSFIFYHES 
361:	FMTNISSWIQ ITLCIIVFSQ FLKAQKIK