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9.B.81 The MceB Immunity Protein (MceB) Family

The MceB protein of Klebsiella pneumoniae protects the cells against the toxic endogenous MceE protein, the precursor of microcin E492, and against this exogenous microcin (Bieler et al., 2006; Lagos et al., 1999; 2001). Its mechanism of action is not known, but it is a cytoplasmic membrane protein with three putative TMSs.

References associated with 9.B.81 family:

Lagos, R., J.E. Villanueva, and O. Monasterio. (1999). Identification and properties of the genes encoding microcin E492 and its immunity protein. J. Bacteriol. 181: 212-217. 9864332
Bieler, S., F. Silva, C. Soto, and D. Belin. (2006). Bactericidal activity of both secreted and nonsecreted microcin E492 requires the mannose permease. J. Bacteriol. 188: 7049-7061. 17015644
Lagos, R., M. Baeza, G. Corsini, C. Hetz, E. Strahsburger, J.A. Castillo, C. Vergara, and O. Monasterio. (2001). Structure, organization and characterization of the gene cluster involved in the production of microcin E492, a channel-forming bacteriocin. Mol. Microbiol. 42: 229-243. 11679081