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9.B.82.1.1
Putative heavy metal transporter, Rer1

Accession Number:P25560
Protein Name:RER1
Length:188
Molecular Weight:22270.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate Metal ions

Cross database links:

Genevestigator: P25560
eggNOG: fuNOG08771
HEGENOM: HBG315333
RefSeq: NP_009925.1   
Entrez Gene ID: 850354   
Pfam: PF03248   
KEGG: sce:YCL001W   

Gene Ontology

GO:0030137 C:COPI-coated vesicle
GO:0030134 C:ER to Golgi transport vesicle
GO:0000139 C:Golgi membrane
GO:0016021 C:integral to membrane
GO:0006888 P:ER to Golgi vesicle-mediated transport
GO:0006621 P:protein retention in ER lumen
GO:0006890 P:retrograde vesicle-mediated transport, Golg...

References (6)

[1] “Membrane protein retrieval from the Golgi apparatus to the endoplasmic reticulum (ER): characterization of the RER1 gene product as a component involved in ER localization of Sec12p.”  Sato K.et.al.   8589449
[2] “The complete DNA sequence of yeast chromosome III.”  Oliver S.G.et.al.   1574125
[3] “Identification of a gene required for membrane protein retention in the early secretory pathway.”  Nishikawa S.et.al.   8367481
[4] “Rer1p as common machinery for the endoplasmic reticulum localization of membrane proteins.”  Sato K.et.al.   9275186
[5] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[6] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDYDSSDTMN GGSSNPLITK MNTMKLLYQH YLDKVTPHAK ERWAVLGGLL CLFMVRITMA 
61:	EGWYVICYGL GLFLLNQFLA FLTPKFDMSL QQDEENNELE AGEKSEEFRP FIRRLPEFKF 
121:	WYNSIRATVI SLLLSLFSIF DIPVFWPILL MYFILLFFLT MRRQIQHMIK YRYIPLDIGK 
181:	KKYSHSSN