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9.B.82.1.2
Putative heavy metal transporter, Rer1

Accession Number:O15258
Protein Name:RER1
Length:196
Molecular Weight:22958.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate Metal ions

Cross database links:

Genevestigator: O15258
eggNOG: prNOG14320
RefSeq: NP_008964.3   
Entrez Gene ID: 11079   
Pfam: PF03248   
KEGG: hsa:11079   

Gene Ontology

GO:0030173 C:integral to Golgi membrane
GO:0006890 P:retrograde vesicle-mediated transport, Golg...

References (6)

[1] “Human Rer1 is localized to the Golgi apparatus and complements the deletion of the homologous Rer1 protein of Saccharomyces cerevisiae.”  Fuellekrug J.et.al.   9309388
[2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[3] “Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.”  Daub H.et.al.   18691976
[4] “A quantitative atlas of mitotic phosphorylation.”  Dephoure N.et.al.   18669648
[5] “Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.”  Gauci S.et.al.   19413330
[6] “Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.”  Mayya V.et.al.   19690332

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSEGDSVGES VHGKPSVVYR FFTRLGQIYQ SWLDKSTPYT AVRWVVTLGL SFVYMIRVYL 
61:	LQGWYIVTYA LGIYHLNLFI AFLSPKVDPS LMEDSDDGPS LPTKQNEEFR PFIRRLPEFK 
121:	FWHAATKGIL VAMVCTFFDA FNVPVFWPIL VMYFIMLFCI TMKRQIKHMI KYRYIPFTHG 
181:	KRRYRGKEDA GKAFAS