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9.B.83.1.1
Potential secretory protein LeoA (may secrete heat labile enterotoxin (LT) from the periplasm) (Brown and Hardwidge, 2007).

Accession Number:Q9RFR9
Protein Name:LeoA
Length:577
Molecular Weight:64941.00
Species:Escherichia coli [562]
Location1 / Topology2 / Orientation3: Secreted1
Substrate proteins

Cross database links:

Pfam: PF01926   

Gene Ontology

GO:0005622 C:intracellular
GO:0005525 F:GTP binding

References (1)

[1] “Identification of a gene within a pathogenicity island of enterotoxigenic Escherichia coli H10407 required for maximal secretion of the heat-labile enterotoxin.”  Fleckenstein J.M.et.al.   10768971

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEQFKQFSIE KQAAINSLLQ LRGMLEMLGE MGINISDDLQ KVTSAINAIE SDVLRIALLG 
61:	AFSDGKTSVI AAWLGKVMDD MNISMDESSD RLSIYKPEGL PDQCEIVDTP GLFGDKEREV 
121:	DGRLVMYEDL TRRYISEAHL IFYVVDATNP LKESHSDIVK WVLRDLNKLS STIFVINKMD 
181:	EVTSLTDQAL FDEQAAIKKA NLKGKLQRAA DLTAQECEQL NIVCVASNPN GRGLTYWFTK 
241:	PEHYESRSRI NDLKNAATEI LKTNVPEVLL VKTGMDVVKD IVIQRVTLAS RHLDELNTFV 
301:	EKNDEDMHRF SNDIKQSRIE VKRLAGELFE ELNLMEKQLM SQLRPLDLDD IRPFMDDELG 
361:	YTEDGVGFKL HLRIKQSVDR FFEQSTAVSQ RLSDDITRQL SSSESFLSGL GEGAFRSLGG 
421:	AFKGVSKISP ATLKTTILAA RDTIGKLTGY VYKFKPWEAT KLAGSIAKWA GPVGAAFTIG 
481:	SDLWDAYKAH EREQELKEVK ASLAKIIKEP FEDIYDVLSS DEKMFAFFAP QIQQMEQVVT 
541:	ELAEKSQAIR DNRQKLSLIQ TQLAQLMVPA TENHTAR