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9.B.97.3.1
Putative isovaleryltransferase, MppN of 456aas and 10 putative TMSs.

Accession Number:Q643C2
Protein Name:Isovaleryltransferase MppN
Length:456
Molecular Weight:50638.00
Species:streptomyces hygroscopicus [1912]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Pfam: PF01757   

Gene Ontology

GO:0016020 C:membrane
GO:0016747 F:transferase activity, transferring acyl gro...

References (1)

[1] “Biosynthetic pathway for mannopeptimycins, lipoglycopeptide antibiotics active against drug-resistant gram-positive pathogens.”  Magarvey N.A.et.al.   16723579

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MWSARKISAK LRRNGGVRLT AARSPRAPWM SGAGDHARII HQPTVVRPPL RRTEPHRLSR 
61:	IWREVRMQTR QSNPNLRSLT GLRFVAMLPV FLTHAAFEGV FSDAKVSWGF LDAMGSTGYM 
121:	AVSFFFVLSG FVITWSYRPT DTARKFWRRR FFRVFPNHVV TYALALGLIA AVGLSVGVLP 
181:	SVTQLFLVQS WVPDPAFTDT GNSVSWSLAV DVVFYALFPV LLTLVNKIKP NRLWYWVGGS 
241:	VIGVAVVPAI ALAALPSTPE MPLGGVSVSQ YWFTYFFPLF RLLECVLGML MARIVLSGKW 
301:	IRLRVLPAAV LVVIAYYFAQ QVPYLYRLSA VTVLPVALLT AAAAVADSEG RGTLFGSKVM 
361:	VWFGELSFAF YLLHNLVLKY GHLLLGHTEE EGELVGHTWG VPEGIALIAA AFAVSLLLAW 
421:	LLHNGVEKQA MRRWSRRKPA PVAEVTSGFY AKDGAI