TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


9.B.97.7.1
The succinyl transferase, MdoC, OpgC or YmdD (formerly DUF418), is of 385 aas and 10 TMSs. Osmoregulated periplasmic glucans (OPGs) of E. coli are anionic oligosaccharides that accumulate in the periplasmic space in response to low osmolarity of the medium. Their anionic character is provided by the substitution of the glucosidic backbone by phosphoglycerol originating from  membrane phospholipids and by succinyl residues from an unknown origin. The mdoC gene is within the mdoGH operon necessary for the synthesis of the OPG backbone (Lacroix et al. 1999). The same is true for Rhodobacter spheroides in which in correspondng operon is the opgGIHC operon (Cogez et al. 2002).

Accession Number:P75920
Protein Name:Glucans biosynthesis protein C
Length:385
Molecular Weight:44690.00
Species:Escherichia coli (strain K12) [83333]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MNPVPAQREY FLDSIRAWLM LLGIPFHISL IYSSHTWHVN SAESSLWLTL FNDFIHSFRM 
61:	QVFFVISGYF SYMLFLRYPL KKWWKVRVER VGIPMLTAIP LLTLPQFIML QYVKGKAESW 
121:	PGLSLYDKYN TLAWELISHL WFLLVLVVMT TLCVWIFKRI RNNLENSDKT NKKFSMVKLS 
181:	VIFLCLGIGY AVIRRTIFIV YPPILSNGMF NFIVMQTLFY LPFFILGALA FIFPHLKALF 
241:	TTPSRGCTLA AALAFVAYLL NQRYGSGDAW MYETESVITM VLGLWMVNVV FSFGHRLLNF 
301:	QSARVTYFVN ASLFIYLVHH PLTLFFGAYI TPHITSNWLG FLCGLIFVVG IAIILYEIHL 
361:	RIPLLKFLFS GKPVVKREND KAPAR