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9.C.13 The Bacterial Endocytosis (BEC) Family

Endocytosis is a process by which extracellular material such as macromolecules can be incorporated into cells via a membrane-trafficking system. Although universal among eukaryotes, endocytosis has only recently been identified in Bacteria or Archaea. Intracellular membranes are known to compartmentalize cells of bacteria in the phylum Planctomycetes, suggesting the potential for endocytosis and membrane trafficking in members of this phylum. Lonhienne et. al, (2010) showed that cells of the planctomycete Gemmata obscuriglobus have the ability to take up proteins present in the external milieu in an energy-dependent process analogous to eukaryotic endocytosis, and that internalized proteins are associated with vesicle membranes. Occurrence of such an ability in a bacterium is consistent with autogenous evolution of endocytosis and the endomembrane system in an ancestral noneukaryotic cell.

References associated with 9.C.13 family:

Lonhienne, T.G., E. Sagulenko, R.I. Webb, K.C. Lee, J. Franke, D.P. Devos, A. Nouwens, B.J. Carroll, and J.A. Fuerst. (2010). Endocytosis-like protein uptake in the bacterium Gemmata obscuriglobus. Proc. Natl. Acad. Sci. USA 107: 12883-12888. 20566852