TCDB is operated by the Saier Lab Bioinformatics Group

Guided Entry of Tail-anchored Protein (GET) Superfamily

In Eukaryotes, tail-anchored proteins use a distinctive pathway for insertion. Animal systems are in TC# 3.A.19 while Fungal systems are in TC#3.A.21.

3.A.19 - The TMS Recognition/Insertion Complex (TRC) Family
3.A.21 - The C-terminal Tail-Anchored Membrane Protein Biogenesis/ Insertion Complex (TAMP-B) Family