1.B.74 The Outer Membrane Beta Barrel L32 Protein (OmpL32) Family
Bacterial protein methylation is a widespread post-translational modification that is required for virulence in many pathogenic bacteria. Methylation of outer-membrane proteins modulates the effectiveness of the host immune response. A Leptospira interrogans surface-exposed β-barrel protein undergoes extensive and differential methylation of glutamic acid residues and was designated OmpL32. Expression of OmpL32 occurs during colonization of liver and kidney (Eshghi et al. 2012). This protein is in the DUF4480 or Peptidase-M14NE family.
The outer membrane β-barrel protein, OmpL32 (Eshghi et al. 2012).
OmpL32 of Leptospira interrogans
Putative porin of 277 aas and 10 - 12 β-strands.
Putative porin of Leptospira biflexa
Putative porin of 242 aas
Putative porin of Turneriella (Leptospira) parva
Putative porin of 306 aas
Putative porin of Leptonema illini