1.E.10 The Bacillus subtilis φ29 Holin (φ29 Holin) Family
Phage φ29 gene 14 encodes the late protein GP14 which is required for phage φ29-promoted host cell lysis. When expressed in E. coli, it leads to cell death without lysis. When expressed together with phage φ29 lysozyme or an unrelated murein-degrading enzyme, cell lysis is also observed. Thus, protein 14 is a nonspecific holin in the cytoplasmic membrane of B. subtilis. It is identical to the phage PZA lysis protein and nearly identical to the phage B103 lysis protein. It is 34% identical to the phage GA-1 holin.
Lysis holin protein (late protein GP14) (Tedin et al. 1995).
Bacillus phage f29
GP14 (131 aas; spP11188)
Pneumococcal phage SV1 holin 1.
Pneumococcal phage SV1 holin 1
Holin HolSMP (Orf43) (Shi et al. 2012).
HolSMP of Streptococcus suis phage SMP