1.E.3 The P2 Holin (P2 Holin) Family

See 1.E for a generalized description of Holins.



This family belongs to the Holin Superfamily III.

 

References:

To, K.H., J. Dewey, J. Weaver, T. Park, and R. Young. (2013). Functional analysis of a class I holin, P2 Y. J. Bacteriol. 195: 1346-1355.

Examples:

TC#NameOrganismal TypeExample
1.E.3.1.1

Lysis protein TM (gene Y product), 93aas; 3 TMSs, N out; C in (predicted).  This holin has been functionally characterized (To et al. 2013).  It's function is counteracted by the anti-holin, LysA.

Phage P2

Lysis protein TM (P51773)

 
1.E.3.1.2

Enterobacterial phage holin family 2 protein, GpY from phage P2

Proteobacterial phage

GpY of phage P2

 
1.E.3.1.3

holin protein of E. coli phage PhiKT

Proteobacterial phage

Holin of phage PhiKT

 
1.E.3.1.4

Phage holin of family 2

Proteobacteria

Phage holin of Burkholderia ambifaria

 
1.E.3.1.5

Putative holin of 96 aas and 3 TMSs

β-Proteobacteria

Putative holin of Achromobacter xylosoxidans

 
Examples:

TC#NameOrganismal TypeExample
1.E.3.2.1

Uncharacterized protein

Actinobacteria

Uncharacterized protein of Mycobacterium avium

 
1.E.3.2.2

Uncharacterized protein (92 aas)

Actinobacteria

Unchazracterized protein of Mycobacterium abscessus

 
Examples:

TC#NameOrganismal TypeExample
1.E.3.3.1

Hypothetical protein; putative porin of 89 aas and 3 TMSs.

Crenarchaea

Hypothetical protein of Pyrolobus fumarii